GPAT 2010 Key Graduate Pharmacy Aptitude Test Answer Key 2010
Q.l The vitamin essential in tissue culture medium is
(A) Pyridoxine (B) Thiamine (C) Nicotinic acid (D) Inositol
Ans. B
Q.2 Gingkgo biloba is used for its
(A) Expectorant activity (B) Lipid lowering activity
(C) PAF antagonistic activity (D)Antidepressant activity
Ans. C
Q.3 The amount of barbaloin present in Aloe vera is
(A) <1% (B) 3.5-4% (c) 1-1.5% (D) 2-2.5%
Ans. B
Q.4 Sildenafil is used for treatment of one of the following disorders :
(A) Systolic hypertension (B) Unstable angina
(C) Pulmonary hypertension (D) Hypertension due to eclampsia
Ans. C
Q.5 Cardiac glycosides have the following configuration in the aglycone part of the steroid nucleus :
(A) 5a, 1 4 a – 5a, 14β- (C) 5β, 1 4 a – (D) 5β,14β-
Ans. D
Q.6 Quassia wood is adulterated with
(A) Brucea antidysentrica (B) Cassia angustifoila
C) Cinnamomum zeylanicum (D) Cephaelis ipecacuanaha
Ans. B
Q.7 Eugenol is present in
(A) Fennel (B) Tulsi (C) Cardamom (D) Coriander
Ans. B
Q.8 Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive
patients with Chronic myeloid Leukemia?
(A) Pentostatin (B) Methotrexate
(C) Imatinib (D) L-Asparaginase
Ans. C
Q.9 Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s
Lymphoma?
(A) Infliximab (B) Abciximab (C) Gemtuzumab (D) Rituximab
Ans.
Q.10 Identify the drug which is NOT used in the treatment of malaria caused by Plasmodium falciparum :
(A.) Artemisinin (B) Primaquine (C) Quinine (D) Mefloquine
Ans. B
Q.ll Which one of the following drugs does NOT act through G-Protein coupled receptors?
(A) Epinephrine (B) Insulin (C) Dopamine (D) TSH
Ans. B
Q.12 Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother
to the foetus?
(A) Lamivudine (B) Zidovudine (C) Indinavir (D) Ribavirin
Ans. B
Q.13 Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in
(A) cholinergic receptors (B) dopaminergic receptors
(C) GABAergic receptors (D) adrenergic receptors
Ans. A
Q.14 Which of the following non-opioid analgesics is a prodrug?
(A) Piroxicam (B) Celecoxib (C)Nabumetone (D) Ketorolac
Ans. C
Q.l The vitamin essential in tissue culture medium is
(A) Pyridoxine (B) Thiamine (C) Nicotinic acid (D) Inositol
Ans. B
Q.2 Gingkgo biloba is used for its
(A) Expectorant activity (B) Lipid lowering activity
(C) PAF antagonistic activity (D)Antidepressant activity
Ans. C
Q.3 The amount of barbaloin present in Aloe vera is
(A) <1% (B) 3.5-4% (c) 1-1.5% (D) 2-2.5%
Ans. B
Q.4 Sildenafil is used for treatment of one of the following disorders :
(A) Systolic hypertension (B) Unstable angina
(C) Pulmonary hypertension (D) Hypertension due to eclampsia
Ans. C
Q.5 Cardiac glycosides have the following configuration in the aglycone part of the steroid nucleus :
(A) 5a, 1 4 a – 5a, 14β- (C) 5β, 1 4 a – (D) 5β,14β-
Ans. D
Q.6 Quassia wood is adulterated with
(A) Brucea antidysentrica (B) Cassia angustifoila
C) Cinnamomum zeylanicum (D) Cephaelis ipecacuanaha
Ans. B
Q.7 Eugenol is present in
(A) Fennel (B) Tulsi (C) Cardamom (D) Coriander
Ans. B
Q.8 Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive
patients with Chronic myeloid Leukemia?
(A) Pentostatin (B) Methotrexate
(C) Imatinib (D) L-Asparaginase
Ans. C
Q.9 Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s
Lymphoma?
(A) Infliximab (B) Abciximab (C) Gemtuzumab (D) Rituximab
Ans.
Q.10 Identify the drug which is NOT used in the treatment of malaria caused by Plasmodium falciparum :
(A.) Artemisinin (B) Primaquine (C) Quinine (D) Mefloquine
Ans. B
Q.ll Which one of the following drugs does NOT act through G-Protein coupled receptors?
(A) Epinephrine (B) Insulin (C) Dopamine (D) TSH
Ans. B
Q.12 Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother
to the foetus?
(A) Lamivudine (B) Zidovudine (C) Indinavir (D) Ribavirin
Ans. B
Q.13 Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in
(A) cholinergic receptors (B) dopaminergic receptors
(C) GABAergic receptors (D) adrenergic receptors
Ans. A
Q.14 Which of the following non-opioid analgesics is a prodrug?
(A) Piroxicam (B) Celecoxib (C)Nabumetone (D) Ketorolac
Ans. C
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